About Me
My personal aim is to advance the treatment of inflammatory diseases, focusing on the inflammatory bowel diseases (IBD) and rheumatoid arthritis (RA). The inflammatory diseases remain poorly understood, limiting the development of treatments and diagnostics. Through my research, I aim to bridge this knowledge-gap and identify disease-specific pathways which can serve as biological targets for treatment, while also increasing our fundamental understanding of the diseases.
My primary biological focus is the innate immune system, particularly the development in newborns and the role of neutrophil granulocytes during inflammatory diseases. I perform comprehensive systems biology (OMICS) characterization of clinical samples from patients and cellular assays, using proteomics, combined with advanced microscopy, bioinformatics, and machine learning/AI.
My efforts aim to extract biological insights, to understand the underlying biology of the pathologies, and ultimately translate this to meaningful advances in treatment options and patient care.
Research Focus
- Investigating the innate immune system's role in IBD and RA, with an emphasis on neutrophils and neutrophil extracellular traps (NETs).
- Understanding the development of the innate immune system in newborns.
- Applying proteomics strategies, bioinformatics and machine learning in immunology
Proteomics
Proteomics is the characterization of the protein composition, the proteome, of a biological sample. While several techniques exists and new continue to emerge, mass spectrometry-driven proteomics remains a widely used core technology in proteomics for large-scale characterization of the proteome. For an review of the commonly applied bottom-up mass spectrometry-driven proteomics workflow, designed to be accessible even to those new to the field please click here.
Publications
For a list of my publications please click here.
Contact
Email: [email protected]
Website: proteomics.dk
Aalborg University Profile
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