About Me
As an Associate Professor at Aalborg University Faculty of Medicine, my work focuses on advancing the treatment of inflammatory diseases by uncovering their molecular mechanisms. Conditions like inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) remain poorly understood, limiting the development of treatments and diagnostics.
My research aims to bridge this knowledge-gap by identifying disease-specific pathways with the potential to advance the treatment of inflammatory diseases. My primary focus is the innate immune system, particularly its development in newborns and the role of neutrophils in inflammatory bowel disease (IBD) and rheumatoid arthritis (RA).
My main methodological approach is comprehensive OMICS characterization, particularly proteomics, of samples from patients, combined with advanced microscopy, bioinformatics, and machine learning. These efforts aim to extract true biological insights from the complex datasets, to understand the underlying biology of the pathologies, and ultimately translate this to meaningful advances in treatment options and patient care.
Research Focus
- Investigating the innate immune system's role in IBD and RA, with an emphasis on neutrophils and neutrophil extracellular traps (NETs).
- Understanding the development of the innate immune system in newborns.
- Applying proteomics strategies, bioinformatics and machine learning in immunology
Proteomics
Proteomics is the characterization of the protein composition, the proteome, of a biological sample. While several techniques exists and new continue to emerge, mass spectrometry-driven proteomics remains a widely used core technology in proteomics for large-scale characterization of the proteome. For an review of the commonly applied bottom-up mass spectrometry-driven proteomics workflow, designed to be accessible even to those new to the field please click here.
Publications
For a list of my publications please click here.
Contact
Email: [email protected]
Website: proteomics.dk
Aalborg University Profile
LinkedIn
Bluesky