Better treatment of inflammatory diseases through comprehensive systems biology characterization (OMICS) - Tue Bjerg Bennike, dr.med., PhD, Ms.c.
As an Associate Professor at Aalborg University's Faculty of Medicine, my work focuses on advancing the treatment of inflammatory diseases by uncovering their molecular mechanisms. Conditions like inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) remain poorly understood at this level, limiting the development of innovative treatments and diagnostics.
My research aims to bridge this gap by characterizing human samples to identify disease-specific pathways. Using OMICS-based strategies, particularly proteomics, I combine advanced bioinformatics and machine learning to analyze complex biological datasets.
My primary focus is the innate immune system, particularly its development in newborns and its role in inflammatory diseases. These efforts aim to analyze high-dimensional biological data to understand the biology underlying pathologies, and ultimately translating this to meaningful advances in tratment options and patient care.
Proteomics is the characterization of the protein composition, the proteome, of a biological sample. While several techniques exists and new continue to emerge, mass spectrometry-driven proteomics remains a widely used core technology in proteomics for large-scale characterization of the proteome. For an review of the commonly applied bottom-up mass spectrometry-driven proteomics workflow, designed to be accessible even to those new to the field please click here.
For a list of my publications please click here.
Email: [email protected]
Website: proteomics.dk
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